IARC revised "Monographs on Ientification of Carcinogenic Hazards to Humans" website (Volumes 1-129)


31 March, 2021.

The International Agency for Research on Cancer (IARC), the cancer agency of the World Health Organization, revised its website "IARC Monographs on the Identification of Carcinogenic Hazards to Humans" on March 26, 2021.

This revision is to notify the publication of the summary results of "Monographs Volume 129: gentian violet, leucogentian violet, malachite green, leucomalachite green, and CI Direct Blue 218".

Gentian violet, leucogentian violet, malachite green, and leucomalachite green have a wide range of uses as dyes and stains, including for textiles, and for biological, medical, forensic, and analytical samples. Gentian violet and malachite green are also antifungal, antiparasitic, and antibacterial agents used in veterinary medicine.

The Working Group evaluated gentian violet, leucomalachite green, and CI Direct Blue 218 as possibly carcinogenic to humans (Group 2B) mainly on the basis of sufficient evidence for cancer in experimental animals. Leucogentian violet and malachite green were each evaluated as not classifiable as to its carcinogenicity to humans (Group 3). For leucogentian violet, evidence regarding cancer in humans, cancer in experimental animals, and carcinogen mechanisms was inadequate because no data were available. For malachite green, there was limited evidence for both cancer in experimental animals and carcinogen mechanisms.

* Note from JEIC:
There is no change in the carcinogenic hazard categories for EMFs.